Untangling Alzheimer’s disease brain
Alzheimer’s disease is a serious disease, the brain circuits involved to get “entangled” in which cognitive problems. Research into the causes and possible treatments for Alzheimer’s disease and intense at the beginning of hope to families affected in the disease.
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A tool that the researchers used widely in a mouse model that is genetically for Alzheimer’s disease in three different genes. More ways to Alzheimer’s disease, but as a gene that increases the risk of contracting the disease does not guarantee anything. Still depends on a number of lifestyle factors including physical activity, nutrition and physical health. However, the mouse model of Alzheimer 3xTg-AD mice called, cover against multiple genes increases the risk and virtually guarantees disease.
Some recent studies have used these mice to study the role of certain specific dietary factors that help or hinder the chances of mice. In the first study of low omega-3 and the ratio of omega-6 fatty acids in the context of the diet of low or high fat content. A second study of vitamin B3 (nicotinamide), to try against some of the mice to develop cognitive problems, Alzheimer’s disease progresses. The brains of fish
Julien et al. Lavel the University of Quebec, published in Neurobiology of Aging, which reported double blow of omega-3 fatty acids and high in fat, it seems that mice genetically susceptible to a fair worse. Unfortunately, the discovery of the diet increases the risk of Alzheimer’s disease is no different from what most Westerners eat.
Many people in North America eat too much saturated fat and not enough omega-3 fat is good for fish. When researchers gave this type of diet of mice with Alzheimer’s, brain of mice that were slightly more markers of the pathology of Alzheimer’s disease. The mockery of nutritional problems, the researchers found that neither high-fat diet or a diet low in omega-3 fatty acids, caused problems. When the two together, the minimum supply omega-3 fatty acids in the context of a diet high in fat, these problems are compounded.
These data are consistent with previous observational studies in humans have shown that people who eat less of the omega-3 fatty acids increased rates of Alzheimer’s disease. Unfortunately, studies have shown successful use of omega-3 supplement in the treatment of Alzheimer’s disease, as it is captured. However, some success in the early treatment of mild dementia. These studies and new data suggest that mice get enough omega-3 fatty acids in the diet before, to help reduce the risk of Alzheimer’s disease later. />
However, there may be good news on the horizon for those who already have Alzheimer’s disease, point on the road. Green et al. al. UC-Irvine published a study in the Journal of Neuroscience, has shown some remarkable effects of vitamin B3, protection of mice genetically predisposed to getting Alzheimer’s disease.
Now before you go out and start feeding it, realize this is a preliminary study using large amounts of vitamin B3. The researchers fed mice is about 100 times the RDA, and 10 times the dose previously shown to cause some toxicity in humans. However, the study is promising, as it helps to reveal some way in which we approach prevents Alzheimer’s disease in high risk populations.
researchers fed the mice with large numbers of AD-3xTg of nicotinamide in the active form of vitamin B3, in their drinking water. These mice performed as well as normal mice, more memory and other cognitive tests. In contrast, mice prone to Alzheimer’s does not get vitamin B3 forecasts showed cognitive decline associated with Alzheimer’s disease. Food Matters
/> The interesting thing in both studies that pave the way for future research on nutritional approaches to treating and preventing Alzheimer’s disease. It is clear that genetics plays a role in some but not all cases of dementia. It is also clear that one should not accept the genetic predisposition in many cases. No destination. They decide to live our lives, including what we choose to eat, and play an important role in the future cognitive.
References:
Journal of Neuroscience (2008), 28 (45): 11500-11510.
Neurobiology of Aging (2008), La Prensa.
Dr. Evans also has a national license Coach Football Federation and the United States more than two decades of coaching experience, allowing you to help people find and use all its potential. Dr. Evans has merged his interests in brain function, health, and training for performance in public seminars and workshops designed to educate the hearing health of the brain and motivate them to take measures to achieve this goal. href =
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