Memory Loss Slurred Speech
Why is Huntington’s an exception?[Biology help..]?
The brain cells of Huntington’s victims slowly degenerate, producing jerking muscles, slurred speech, swallowing difficulty, loss of balance, mood swings, reasoning and memory loss, incapacitation, and eventually death (usually from pneumonia or heart failure).
The onset of Huntington’s disease is typically 35 to 45 years.
It is caused by a repeated DNA sequence (AGC). The normal allele has 11-34 copies; affected people have 42 – 120 copies.
The severity and time of onset depends on the number of repeats.
People who are most at risk inherit the gene from their father. This is an example of genomic imprinting.
The gene is on chromosome 4. A diagnostic test is available.
It is due to an autosomal dominant allele.
People who are most at risk inherit the gene from their father. This is an example of genomic imprinting – not true – Most genes in the body are present in two copies: one from your mother and one from your father. The gene that causes Huntington’s disease is dominant. This means that if you inherit a copy of this gene from either parent, you will go on to develop the disease at some point in your life.
Additional Information
- Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a [Neuroscience] « Science JournalFeeds
- Stroke (Brain Attack) Part VII – How to Prevent Stroke With Nutritional Supplements — http://chet-thansamai.co.cc/
- The insemination race: Running against spermatozoons | Sistema Limbico
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